{"id":13838,"date":"2026-02-16T16:05:12","date_gmt":"2026-02-16T12:35:12","guid":{"rendered":"https:\/\/daroom.ir\/blog\/?p=13838"},"modified":"2026-02-24T17:33:30","modified_gmt":"2026-02-24T14:03:30","slug":"xgeva-denosumab-bone-metastasis","status":"publish","type":"post","link":"https:\/\/daroom.ir\/blog\/xgeva-denosumab-bone-metastasis\/","title":{"rendered":"\u0646\u0642\u0634 \u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 (Xgeva) \u062f\u0631 \u062f\u0631\u0645\u0627\u0646 \u0645\u062a\u0627\u0633\u062a\u0627\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0686\u06cc\u0633\u062a\u061f"},"content":{"rendered":"

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\u0627\u06cc\u0646 \u062f\u0627\u0631\u0648 \u062f\u0631\u0645\u0627\u0646 \u0645\u0633\u062a\u0642\u06cc\u0645 \u0633\u0631\u0637\u0627\u0646 \u0645\u062d\u0633\u0648\u0628 \u0646\u0645\u06cc\u200c\u0634\u0648\u062f. \u0646\u0642\u0634 \u0622\u0646\u060c \u0645\u062f\u06cc\u0631\u06cc\u062a \u0639\u0648\u0627\u0631\u0636 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0646\u0627\u0634\u06cc \u0627\u0632 \u0633\u0631\u0637\u0627\u0646 \u0627\u0633\u062a\u061b \u0645\u0648\u0636\u0648\u0639\u06cc \u06a9\u0647 \u062f\u0631 \u06a9\u06cc\u0641\u06cc\u062a \u0632\u0646\u062f\u06af\u06cc \u0628\u06cc\u0645\u0627\u0631 \u0646\u0642\u0634 \u062a\u0639\u06cc\u06cc\u0646\u200c\u06a9\u0646\u0646\u062f\u0647 \u062f\u0627\u0631\u062f.<\/p>\n

\"\u062f\u0627\u0631\u0648\u062e\u0627\u0646\u0647<\/a><\/p>\n

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\"\u062a\u0632\u0631\u06cc\u0642<\/p>\n

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\u0628\u0627 \u0648\u062c\u0648\u062f \u0634\u0628\u0627\u0647\u062a \u0645\u0627\u062f\u0647 \u0645\u0624\u062b\u0631\u060c \u0627\u06cc\u0646 \u062f\u0648 \u062f\u0627\u0631\u0648 \u062c\u0627\u06cc\u06af\u0632\u06cc\u0646 \u0645\u0633\u062a\u0642\u06cc\u0645 \u06cc\u06a9\u062f\u06cc\u06af\u0631 \u0646\u06cc\u0633\u062a\u0646\u062f \u0648 \u0627\u0646\u062a\u062e\u0627\u0628 \u0622\u0646\u200c\u0647\u0627 \u06a9\u0627\u0645\u0644\u0627\u064b \u0648\u0627\u0628\u0633\u062a\u0647 \u0628\u0647 \u0634\u0631\u0627\u06cc\u0637 \u0628\u06cc\u0645\u0627\u0631 \u0648 \u062a\u0634\u062e\u06cc\u0635 \u067e\u0632\u0634\u06a9 \u0627\u0633\u062a.<\/p>\n

\u0645\u0642\u0627\u06cc\u0633\u0647 \u0627\u06a9\u0633\u062c\u0648\u0627 \u0628\u0627 \u0632\u0648\u0644\u062f\u0631\u0648\u0646\u06cc\u06a9 \u0627\u0633\u06cc\u062f<\/h2>\n

\u062f\u0631 \u0645\u0642\u0627\u06cc\u0633\u0647 \u0628\u0627 \u0632\u0648\u0644\u062f\u0631\u0648\u0646\u06cc\u06a9 \u0627\u0633\u06cc\u062f \u06a9\u0647 \u0627\u0632 \u06af\u0631\u0648\u0647 \u0628\u06cc\u0633\u200c\u0641\u0633\u0641\u0648\u0646\u0627\u062a\u200c\u0647\u0627\u0633\u062a\u060c \u0627\u06a9\u0633\u062c\u0648\u0627 \u062f\u0631 \u0628\u0631\u062e\u06cc \u0645\u0637\u0627\u0644\u0639\u0627\u062a \u062a\u0648\u0627\u0646\u0633\u062a\u0647 \u0632\u0645\u0627\u0646 \u0628\u0631\u0648\u0632 \u0627\u0648\u0644\u06cc\u0646 \u0639\u0627\u0631\u0636\u0647 \u0627\u0633\u06a9\u0644\u062a\u06cc \u0631\u0627 \u0686\u0646\u062f \u0645\u0627\u0647 \u0628\u06cc\u0634\u062a\u0631 \u0628\u0647 \u062a\u0623\u062e\u06cc\u0631 \u0628\u06cc\u0646\u062f\u0627\u0632\u062f. \u06cc\u06a9\u06cc \u0627\u0632 \u062a\u0641\u0627\u0648\u062a\u200c\u0647\u0627\u06cc \u0645\u0647\u0645 \u0627\u06cc\u0646 \u0627\u0633\u062a \u06a9\u0647 \u0632\u0648\u0644\u062f\u0631\u0648\u0646\u06cc\u06a9 \u0627\u0633\u06cc\u062f \u0645\u062d\u062f\u0648\u062f\u06cc\u062a\u200c\u0647\u0627\u06cc \u0628\u06cc\u0634\u062a\u0631\u06cc \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 \u0646\u0627\u0631\u0633\u0627\u06cc\u06cc \u06a9\u0644\u06cc\u0648\u06cc \u062f\u0627\u0631\u062f\u060c \u062f\u0631 \u062d\u0627\u0644\u06cc \u06a9\u0647 \u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 \u062f\u0631 \u0627\u06cc\u0646 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0642\u0627\u0628\u0644 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0633\u062a\u060c \u0627\u0644\u0628\u062a\u0647 \u0628\u0627 \u067e\u0627\u06cc\u0634 \u062f\u0642\u06cc\u0642 \u06a9\u0644\u0633\u06cc\u0645.<\/p>\n

\u0627\u0646\u062a\u062e\u0627\u0628 \u0628\u06cc\u0646 \u0627\u06cc\u0646 \u062f\u0648 \u062f\u0631\u0645\u0627\u0646 \u06a9\u0627\u0645\u0644\u0627\u064b \u0628\u0647 \u0648\u0636\u0639\u06cc\u062a \u0628\u0627\u0644\u06cc\u0646\u06cc \u0628\u06cc\u0645\u0627\u0631\u060c \u0639\u0645\u0644\u06a9\u0631\u062f \u06a9\u0644\u06cc\u0647 \u0648 \u0646\u0638\u0631 \u0645\u062a\u062e\u0635\u0635 \u0627\u0646\u06a9\u0648\u0644\u0648\u0698\u06cc \u0628\u0633\u062a\u06af\u06cc \u062f\u0627\u0631\u062f.<\/p>\n

\u062f\u0633\u062a\u0631\u0633\u06cc \u0648 \u062a\u0647\u06cc\u0647 \u0627\u06a9\u0633\u062c\u0648\u0627 \u0627\u0632 \u0637\u0631\u06cc\u0642 \u062f\u0627\u0631\u0648\u062e\u0627\u0646\u0647 \u0622\u0646\u0644\u0627\u06cc\u0646<\/h2>\n

\u0627\u06a9\u0633\u062c\u0648\u0627 \u062c\u0632\u0648 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u062a\u062e\u0635\u0635\u06cc \u0648 \u06af\u0627\u0647\u06cc \u06a9\u0645\u06cc\u0627\u0628 \u0645\u062d\u0633\u0648\u0628 \u0645\u06cc\u200c\u0634\u0648\u062f \u0648 \u0628\u0633\u06cc\u0627\u0631\u06cc \u0627\u0632 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u062f\u0631\u0628\u0627\u0631\u0647 \u0646\u062d\u0648\u0647 \u062a\u0647\u06cc\u0647 \u0622\u0646 \u0633\u0624\u0627\u0644 \u062f\u0627\u0631\u0646\u062f.<\/p>\n

\u0627\u0645\u06a9\u0627\u0646 \u062e\u0631\u06cc\u062f \u0622\u0646\u0644\u0627\u06cc\u0646 \u062f\u0627\u0631\u0648 \u0648 \u0633\u0641\u0627\u0631\u0634 \u0627\u06cc\u0646\u062a\u0631\u0646\u062a\u06cc \u062f\u0627\u0631\u0648 \u062f\u0631 \u062a\u0647\u0631\u0627\u0646 \u0648 \u0633\u0627\u06cc\u0631 \u0634\u0647\u0631\u0647\u0627 \u0628\u0631\u0627\u06cc \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u062a\u062e\u0635\u0635\u06cc \u0628\u0627 \u0646\u0633\u062e\u0647 \u06cc\u0627 \u0628\u062f\u0648\u0646 \u0646\u0633\u062e\u0647 \u0641\u0631\u0627\u0647\u0645 \u0634\u062f\u0647 \u0627\u0633\u062a. \u062e\u062f\u0645\u0627\u062a\u06cc \u0645\u0627\u0646\u0646\u062f \u0627\u0631\u0633\u0627\u0644 \u062f\u0627\u0631\u0648 \u062f\u0631\u0628 \u0645\u0646\u0632\u0644 \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0628\u0627 \u0645\u062d\u062f\u0648\u062f\u06cc\u062a \u062d\u0631\u06a9\u062a\u06cc \u0627\u0647\u0645\u06cc\u062a \u0632\u06cc\u0627\u062f\u06cc \u062f\u0627\u0631\u062f. \u062f\u0627\u0631\u0648\u062e\u0627\u0646\u0647 \u0622\u0646\u0644\u0627\u06cc\u0646 \u062f\u0627\u0631\u0648\u0645<\/a> \u062a\u0644\u0627\u0634 \u0645\u06cc\u200c\u06a9\u0646\u062f \u0641\u0631\u0622\u06cc\u0646\u062f \u062e\u0631\u06cc\u062f \u0627\u06cc\u0646\u062a\u0631\u0646\u062a\u06cc \u062f\u0627\u0631\u0648 \u0631\u0627 \u062a\u062d\u062a \u0646\u0638\u0627\u0631\u062a \u062f\u0627\u0631\u0648\u0633\u0627\u0632 \u0648 \u0645\u0637\u0627\u0628\u0642 \u0628\u0627 \u0636\u0648\u0627\u0628\u0637 \u0642\u0627\u0646\u0648\u0646\u06cc \u0627\u0646\u062c\u0627\u0645 \u062f\u0647\u062f\u060c \u0628\u0647\u200c\u062e\u0635\u0648\u0635 \u062f\u0631 \u0645\u0648\u0631\u062f \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u06a9\u0645\u06cc\u0627\u0628 \u06a9\u0647 \u0646\u06cc\u0627\u0632 \u0628\u0647 \u067e\u06cc\u06af\u06cc\u0631\u06cc \u062f\u0642\u06cc\u0642\u200c\u062a\u0631\u06cc \u062f\u0627\u0631\u0646\u062f.<\/p>\n

\u062f\u0631 \u0645\u0648\u0631\u062f \u0627\u06a9\u0633\u062c\u0648\u0627 \u0646\u06cc\u0632 \u0627\u0631\u0627\u0626\u0647 \u062f\u0627\u0631\u0648 \u062a\u0646\u0647\u0627 \u0628\u0627 \u0646\u0633\u062e\u0647 \u0645\u0639\u062a\u0628\u0631 \u067e\u0632\u0634\u06a9 \u0627\u0646\u062c\u0627\u0645 \u0645\u06cc\u200c\u0634\u0648\u062f \u0648 \u0628\u0631\u0631\u0633\u06cc \u0645\u0648\u062c\u0648\u062f\u06cc \u0648 \u0634\u0631\u0627\u06cc\u0637 \u062a\u0648\u0632\u06cc\u0639 \u0646\u0642\u0634 \u0645\u0647\u0645\u06cc \u062f\u0631 \u062f\u0633\u062a\u0631\u0633\u06cc \u062f\u0627\u0631\u062f.<\/p>\n

\u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 (Xgeva) \u06cc\u06a9 \u062f\u0631\u0645\u0627\u0646 \u0647\u062f\u0641\u0645\u0646\u062f \u0628\u0631\u0627\u06cc \u06a9\u0646\u062a\u0631\u0644 \u0639\u0648\u0627\u0631\u0636 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0646\u0627\u0634\u06cc \u0627\u0632 \u0633\u0631\u0637\u0627\u0646 \u0627\u0633\u062a. \u0627\u06cc\u0646 \u062f\u0627\u0631\u0648 \u0628\u0627 \u0645\u0647\u0627\u0631 \u0645\u0633\u06cc\u0631 RANKL\u060c \u0633\u0631\u0639\u062a \u062a\u062e\u0631\u06cc\u0628 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0631\u0627 \u06a9\u0627\u0647\u0634 \u0645\u06cc\u200c\u062f\u0647\u062f \u0648 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u062e\u0637\u0631 \u0634\u06a9\u0633\u062a\u06af\u06cc \u0648 \u0646\u06cc\u0627\u0632 \u0628\u0647 \u0645\u062f\u0627\u062e\u0644\u0627\u062a \u0627\u0633\u06a9\u0644\u062a\u06cc \u0631\u0627 \u06a9\u0645\u062a\u0631 \u06a9\u0646\u062f. \u062f\u0631 \u0639\u06cc\u0646 \u062d\u0627\u0644\u060c \u0645\u0635\u0631\u0641 \u0622\u0646 \u0646\u06cc\u0627\u0632\u0645\u0646\u062f \u067e\u0627\u06cc\u0634 \u062f\u0642\u06cc\u0642 \u0622\u0632\u0645\u0627\u06cc\u0634\u06af\u0627\u0647\u06cc\u060c \u062a\u0648\u062c\u0647 \u0628\u0647 \u0633\u0644\u0627\u0645\u062a \u062f\u0647\u0627\u0646 \u0648 \u062f\u0646\u062f\u0627\u0646 \u0648 \u0642\u0637\u0639 \u0627\u0635\u0648\u0644\u06cc \u062f\u0631\u0645\u0627\u0646 \u0627\u0633\u062a.<\/p>\n

\u062a\u0635\u0645\u06cc\u0645\u200c\u06af\u06cc\u0631\u06cc \u062f\u0631\u0628\u0627\u0631\u0647 \u0634\u0631\u0648\u0639 \u06cc\u0627 \u0627\u062f\u0627\u0645\u0647 \u0627\u06a9\u0633\u062c\u0648\u0627 \u0628\u0627\u06cc\u062f \u06a9\u0627\u0645\u0644\u0627\u064b \u062a\u0648\u0633\u0637 \u0645\u062a\u062e\u0635\u0635 \u0627\u0646\u062c\u0627\u0645 \u0634\u0648\u062f. \u0622\u06af\u0627\u0647\u06cc \u0628\u06cc\u0645\u0627\u0631 \u0627\u0632 \u0645\u06a9\u0627\u0646\u06cc\u0633\u0645 \u0627\u062b\u0631\u060c \u0639\u0648\u0627\u0631\u0636 \u0648 \u0647\u0634\u062f\u0627\u0631\u0647\u0627 \u06a9\u0645\u06a9 \u0645\u06cc\u200c\u06a9\u0646\u062f \u062f\u0631\u0645\u0627\u0646 \u0628\u0627 \u0627\u0637\u0645\u06cc\u0646\u0627\u0646 \u0628\u06cc\u0634\u062a\u0631\u06cc \u067e\u06cc\u0634 \u0628\u0631\u0648\u062f.<\/p>\n

\u0633\u0648\u0627\u0644\u0627\u062a \u0645\u062a\u062f\u0627\u0648\u0644 \u062f\u0631\u0628\u0627\u0631\u0647 \u0627\u06a9\u0633\u062c\u0648\u0627<\/h2>\n

1. \u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 \u0628\u0631\u0627\u06cc \u0686\u0647 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646\u06cc \u0645\u0646\u0627\u0633\u0628 \u0627\u0633\u062a\u061f<\/h3>\n

\u0627\u06cc\u0646 \u062f\u0627\u0631\u0648 \u0645\u0639\u0645\u0648\u0644\u0627\u064b \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0628\u062a\u0644\u0627 \u0628\u0647 \u0633\u0631\u0637\u0627\u0646 \u0628\u0627 \u0645\u062a\u0627\u0633\u062a\u0627\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc\u060c \u0645\u0648\u0644\u062a\u06cc\u067e\u0644 \u0645\u06cc\u0644\u0648\u0645\u0627 \u06cc\u0627 \u0647\u0627\u06cc\u067e\u0631\u06a9\u0644\u0633\u0645\u06cc \u0646\u0627\u0634\u06cc \u0627\u0632 \u0628\u062f\u062e\u06cc\u0645\u06cc \u062a\u062c\u0648\u06cc\u0632 \u0645\u06cc\u200c\u0634\u0648\u062f \u0648 \u0647\u062f\u0641 \u0622\u0646 \u06a9\u0627\u0647\u0634 \u0639\u0648\u0627\u0631\u0636 \u0627\u0633\u06a9\u0644\u062a\u06cc \u0627\u0633\u062a.<\/p>\n

2. \u0622\u06cc\u0627 \u0627\u06a9\u0633\u062c\u0648\u0627 \u0633\u0631\u0637\u0627\u0646 \u0631\u0627 \u062f\u0631\u0645\u0627\u0646 \u0645\u06cc\u200c\u06a9\u0646\u062f\u061f<\/h3>\n

\u062e\u06cc\u0631. \u0627\u06cc\u0646 \u062f\u0627\u0631\u0648 \u062f\u0631\u0645\u0627\u0646 \u0645\u0633\u062a\u0642\u06cc\u0645 \u062a\u0648\u0645\u0648\u0631 \u0646\u06cc\u0633\u062a \u0628\u0644\u06a9\u0647 \u0628\u0631\u0627\u06cc \u06a9\u0646\u062a\u0631\u0644 \u0639\u0648\u0627\u0631\u0636 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0646\u0627\u0634\u06cc \u0627\u0632 \u0633\u0631\u0637\u0627\u0646 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f.<\/p>\n

3. \u062a\u0632\u0631\u06cc\u0642 \u0627\u06a9\u0633\u062c\u0648\u0627 \u0686\u0646\u062f \u0648\u0642\u062a \u06cc\u06a9\u0628\u0627\u0631 \u0627\u0646\u062c\u0627\u0645 \u0645\u06cc\u200c\u0634\u0648\u062f\u061f<\/h3>\n

\u062f\u0631 \u0627\u063a\u0644\u0628 \u0645\u0648\u0627\u0631\u062f \u0647\u0631 \u0686\u0647\u0627\u0631 \u0647\u0641\u062a\u0647 \u06cc\u06a9\u0628\u0627\u0631 \u062a\u0632\u0631\u06cc\u0642 \u0632\u06cc\u0631\u062c\u0644\u062f\u06cc \u0627\u0646\u062c\u0627\u0645 \u0645\u06cc\u200c\u0634\u0648\u062f\u060c \u0645\u06af\u0631 \u062f\u0631 \u0634\u0631\u0627\u06cc\u0637 \u062e\u0627\u0635 \u06a9\u0647 \u0628\u0631\u0646\u0627\u0645\u0647 \u0645\u062a\u0641\u0627\u0648\u062a\u06cc \u062a\u062c\u0648\u06cc\u0632 \u0634\u0648\u062f.<\/p>\n

4. \u0622\u06cc\u0627 \u0627\u0645\u06a9\u0627\u0646 \u062a\u0632\u0631\u06cc\u0642 \u062f\u0631 \u062e\u0627\u0646\u0647 \u0648\u062c\u0648\u062f \u062f\u0627\u0631\u062f\u061f<\/h3>\n

\u062a\u0632\u0631\u06cc\u0642 \u0628\u0627\u06cc\u062f \u062a\u0648\u0633\u0637 \u06a9\u0627\u062f\u0631 \u062f\u0631\u0645\u0627\u0646 \u0627\u0646\u062c\u0627\u0645 \u0634\u0648\u062f \u062a\u0627 \u062f\u0648\u0632\u060c \u0634\u0631\u0627\u06cc\u0637 \u0646\u06af\u0647\u062f\u0627\u0631\u06cc \u0648 \u0627\u06cc\u0645\u0646\u06cc \u0631\u0639\u0627\u06cc\u062a \u0634\u0648\u062f.<\/p>\n

5. \u0645\u0647\u0645\u200c\u062a\u0631\u06cc\u0646 \u0639\u0627\u0631\u0636\u0647 \u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 \u0686\u06cc\u0633\u062a\u061f<\/h3>\n

\u06a9\u0627\u0647\u0634 \u0633\u0637\u062d \u06a9\u0644\u0633\u06cc\u0645 \u062e\u0648\u0646 \u0627\u0632 \u0645\u0647\u0645\u200c\u062a\u0631\u06cc\u0646 \u0639\u0648\u0627\u0631\u0636 \u0627\u0633\u062a \u0648 \u0646\u06cc\u0627\u0632 \u0628\u0647 \u067e\u0627\u06cc\u0634 \u0622\u0632\u0645\u0627\u06cc\u0634\u06af\u0627\u0647\u06cc \u062f\u0627\u0631\u062f.<\/p>\n

6. \u0622\u06cc\u0627 \u0642\u0637\u0639 \u0646\u0627\u06af\u0647\u0627\u0646\u06cc \u062f\u0627\u0631\u0648 \u062e\u0637\u0631\u0646\u0627\u06a9 \u0627\u0633\u062a\u061f<\/h3>\n

\u0628\u0644\u0647. \u0642\u0637\u0639 \u0646\u0627\u06af\u0647\u0627\u0646\u06cc \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u062e\u0637\u0631 \u0634\u06a9\u0633\u062a\u06af\u06cc \u0645\u0647\u0631\u0647\u200c\u0627\u06cc \u0631\u0627 \u0627\u0641\u0632\u0627\u06cc\u0634 \u062f\u0647\u062f \u0648 \u0628\u0627\u06cc\u062f \u062a\u062d\u062a \u0646\u0638\u0631 \u067e\u0632\u0634\u06a9 \u0627\u0646\u062c\u0627\u0645 \u0634\u0648\u062f.<\/p>\n

7. \u0622\u06cc\u0627 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u06a9\u0644\u06cc\u0648\u06cc \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u0646\u062f \u0627\u0632 \u0627\u06a9\u0633\u062c\u0648\u0627 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u06a9\u0646\u0646\u062f\u061f<\/h3>\n

\u062f\u0631 \u0628\u0633\u06cc\u0627\u0631\u06cc \u0627\u0632 \u0645\u0648\u0627\u0631\u062f \u0628\u0644\u0647\u060c \u0627\u0645\u0627 \u0628\u0627 \u067e\u0627\u06cc\u0634 \u062f\u0642\u06cc\u0642 \u0633\u0637\u062d \u06a9\u0644\u0633\u06cc\u0645 \u0648 \u062a\u062d\u062a \u0646\u0638\u0631 \u067e\u0632\u0634\u06a9.<\/p>\n

8. \u062a\u0641\u0627\u0648\u062a \u0627\u06a9\u0633\u062c\u0648\u0627 \u0648 \u067e\u0631\u0648\u0644\u06cc\u0627 \u062f\u0631 \u0686\u06cc\u0633\u062a\u061f<\/h3>\n

\u0647\u0631 \u062f\u0648 \u062d\u0627\u0648\u06cc \u062f\u0646\u0648\u0632\u0648\u0645\u0627\u0628 \u0647\u0633\u062a\u0646\u062f \u0627\u0645\u0627 \u062f\u0648\u0632 \u0648 \u06a9\u0627\u0631\u0628\u0631\u062f \u062f\u0631\u0645\u0627\u0646\u06cc \u0622\u0646\u200c\u0647\u0627 \u0645\u062a\u0641\u0627\u0648\u062a \u0627\u0633\u062a.<\/p>\n

9. \u0622\u06cc\u0627 \u0646\u06cc\u0627\u0632 \u0628\u0647 \u0645\u06a9\u0645\u0644 \u0647\u0645\u0632\u0645\u0627\u0646 \u0648\u062c\u0648\u062f \u062f\u0627\u0631\u062f\u061f<\/h3>\n

\u062f\u0631 \u0627\u063a\u0644\u0628 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0635\u0631\u0641 \u06a9\u0644\u0633\u06cc\u0645 \u0648 \u0648\u06cc\u062a\u0627\u0645\u06cc\u0646 D \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f \u062a\u0627 \u062e\u0637\u0631 \u0647\u06cc\u067e\u0648\u06a9\u0644\u0633\u0645\u06cc \u06a9\u0627\u0647\u0634 \u06cc\u0627\u0628\u062f.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 (Xgeva) \u0646\u0627\u0645 \u062a\u062c\u0627\u0631\u06cc \u062f\u0646\u0648\u0632\u0648\u0645\u0627\u0628 \u0628\u0627 \u062f\u0648\u0632 \u06f1\u06f2\u06f0 \u0645\u06cc\u0644\u06cc\u200c\u06af\u0631\u0645 \u0627\u0633\u062a\u061b \u06cc\u06a9 \u0622\u0646\u062a\u06cc\u200c\u0628\u0627\u062f\u06cc \u0645\u0648\u0646\u0648\u06a9\u0644\u0648\u0646\u0627\u0644 \u0627\u0646\u0633\u0627\u0646\u06cc \u06a9\u0647 \u0628\u0631\u0627\u06cc \u06a9\u0646\u062a\u0631\u0644 \u062a\u062e\u0631\u06cc\u0628 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0628\u062a\u0644\u0627 \u0628\u0647 \u0633\u0631\u0637\u0627\u0646 \u062a\u062c\u0648\u06cc\u0632 \u0645\u06cc\u200c\u0634\u0648\u062f. \u0648\u0642\u062a\u06cc \u0633\u0631\u0637\u0627\u0646 \u0628\u0647 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u06af\u0633\u062a\u0631\u0634 \u067e\u06cc\u062f\u0627 \u0645\u06cc\u200c\u06a9\u0646\u062f\u060c \u062a\u0639\u0627\u062f\u0644 \u0637\u0628\u06cc\u0639\u06cc \u0628\u0627\u0632\u0633\u0627\u0632\u06cc \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0628\u0647 \u0647\u0645 \u0645\u06cc\u200c\u062e\u0648\u0631\u062f. \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u062a\u062e\u0631\u06cc\u0628\u200c\u06a9\u0646\u0646\u062f\u0647 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0628\u06cc\u0634\u200c\u0641\u0639\u0627\u0644 \u0645\u06cc\u200c\u0634\u0648\u0646\u062f \u0648 \u0646\u062a\u06cc\u062c\u0647 \u0622\u0646 \u062f\u0631\u062f\u060c \u0636\u0639\u0641 \u0633\u0627\u062e\u062a\u0627\u0631 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0648 \u0627\u0641\u0632\u0627\u06cc\u0634 […]<\/p>\n","protected":false},"author":1,"featured_media":13846,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[76,75],"tags":[],"class_list":["post-13838","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-information","category-medicine-health-services"],"yoast_head":"\n\u0646\u0642\u0634 \u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 (Xgeva) \u062f\u0631 \u062f\u0631\u0645\u0627\u0646 \u0645\u062a\u0627\u0633\u062a\u0627\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0686\u06cc\u0633\u062a\u061f - Daroom\/Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/daroom.ir\/blog\/xgeva-denosumab-bone-metastasis\/\" \/>\n<meta property=\"og:locale\" content=\"fa_IR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0646\u0642\u0634 \u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 (Xgeva) \u062f\u0631 \u062f\u0631\u0645\u0627\u0646 \u0645\u062a\u0627\u0633\u062a\u0627\u0632 \u0627\u0633\u062a\u062e\u0648\u0627\u0646\u06cc \u0686\u06cc\u0633\u062a\u061f\" \/>\n<meta property=\"og:description\" content=\"\u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 (Xgeva) \u0646\u0627\u0645 \u062a\u062c\u0627\u0631\u06cc \u062f\u0646\u0648\u0632\u0648\u0645\u0627\u0628 \u0628\u0627 \u062f\u0648\u0632 \u06f1\u06f2\u06f0 \u0645\u06cc\u0644\u06cc\u200c\u06af\u0631\u0645 \u0627\u0633\u062a\u061b \u06cc\u06a9 \u0622\u0646\u062a\u06cc\u200c\u0628\u0627\u062f\u06cc \u0645\u0648\u0646\u0648\u06a9\u0644\u0648\u0646\u0627\u0644 \u0627\u0646\u0633\u0627\u0646\u06cc \u06a9\u0647 \u0628\u0631\u0627\u06cc \u06a9\u0646\u062a\u0631\u0644 \u062a\u062e\u0631\u06cc\u0628 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0645\u0628\u062a\u0644\u0627 \u0628\u0647 \u0633\u0631\u0637\u0627\u0646 \u062a\u062c\u0648\u06cc\u0632 \u0645\u06cc\u200c\u0634\u0648\u062f. \u0648\u0642\u062a\u06cc \u0633\u0631\u0637\u0627\u0646 \u0628\u0647 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u06af\u0633\u062a\u0631\u0634 \u067e\u06cc\u062f\u0627 \u0645\u06cc\u200c\u06a9\u0646\u062f\u060c \u062a\u0639\u0627\u062f\u0644 \u0637\u0628\u06cc\u0639\u06cc \u0628\u0627\u0632\u0633\u0627\u0632\u06cc \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0628\u0647 \u0647\u0645 \u0645\u06cc\u200c\u062e\u0648\u0631\u062f. \u0633\u0644\u0648\u0644\u200c\u0647\u0627\u06cc \u062a\u062e\u0631\u06cc\u0628\u200c\u06a9\u0646\u0646\u062f\u0647 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0628\u06cc\u0634\u200c\u0641\u0639\u0627\u0644 \u0645\u06cc\u200c\u0634\u0648\u0646\u062f \u0648 \u0646\u062a\u06cc\u062c\u0647 \u0622\u0646 \u062f\u0631\u062f\u060c \u0636\u0639\u0641 \u0633\u0627\u062e\u062a\u0627\u0631 \u0627\u0633\u062a\u062e\u0648\u0627\u0646 \u0648 \u0627\u0641\u0632\u0627\u06cc\u0634 […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/daroom.ir\/blog\/xgeva-denosumab-bone-metastasis\/\" \/>\n<meta property=\"og:site_name\" content=\"Daroom\/Blog\" \/>\n<meta property=\"article:author\" content=\"#\" \/>\n<meta property=\"article:published_time\" content=\"2026-02-16T12:35:12+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-24T14:03:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/daroom.ir\/blog\/wp-content\/uploads\/2026\/02\/xgeva.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"750\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"\u062f\u06a9\u062a\u0631 \u062d\u0633\u06cc\u0646 \u062e\u0644\u06cc\u0644\u06cc\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@#\" \/>\n<meta name=\"twitter:label1\" content=\"\u0646\u0648\u0634\u062a\u0647\u200c\u0634\u062f\u0647 \u0628\u062f\u0633\u062a\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u062f\u06a9\u062a\u0631 \u062d\u0633\u06cc\u0646 \u062e\u0644\u06cc\u0644\u06cc\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/daroom.ir\\\/blog\\\/xgeva-denosumab-bone-metastasis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/daroom.ir\\\/blog\\\/xgeva-denosumab-bone-metastasis\\\/\"},\"author\":{\"name\":\"\u062f\u06a9\u062a\u0631 \u062d\u0633\u06cc\u0646 \u062e\u0644\u06cc\u0644\u06cc\",\"@id\":\"https:\\\/\\\/daroom.ir\\\/blog\\\/#\\\/schema\\\/person\\\/ba20b4858309175447d6ed7fb6416011\"},\"headline\":\"\u0646\u0642\u0634 \u0622\u0645\u067e\u0648\u0644 \u0627\u06a9\u0633\u062c\u0648\u0627 (Xgeva) 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